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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">radiology</journal-id><journal-title-group><journal-title xml:lang="ru">Радиология — практика</journal-title><trans-title-group xml:lang="en"><trans-title>Radiology - Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2713-0118</issn><publisher><publisher-name>Центральный научно-исследовательский институт лучевой диагностики</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">radiology-55</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Прогнозирование патологического ответа на неоадъювантную химиотерапию при местно-распространенном раке желудка по данным компьютерно-томографической волюметрии</article-title><trans-title-group xml:lang="en"><trans-title>Predicting of Pathologic Response to Neoadjuvant Chemotherapy in Locally-advanced Gastric Cancer by Volumetric Computed Tomography</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клименко</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Klimenko</surname><given-names>A. O.</given-names></name></name-alternatives><email xlink:type="simple">annaklimenko25@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синицын</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinitsyn</surname><given-names>V. E.</given-names></name></name-alternatives><email xlink:type="simple">vsini@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шрайнер</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shrainer</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">shrainer@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мершина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mershina</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">Elena_mershina@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лядов</surname><given-names>В. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyadov</surname><given-names>V. K.</given-names></name></name-alternatives><email xlink:type="simple">vlyadov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петровичев</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrovichev</surname><given-names>V. S.</given-names></name></name-alternatives><email xlink:type="simple">petrovi4ev@gmail.com</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuing Professional Education, Ministry of Healthcare of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Московский государственный университет им. М. В. Ломоносова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Lomonosov Moscow State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ г. Москвы «Городская клиническая больница № 1 им. Н. И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov's City Clinical Hospital №1, Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГАУ «Лечебно-реабилитационный центр» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Center of Treatment and Rehabilitation Ministry of Healthcare of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2019</year></pub-date><volume>0</volume><issue>3</issue><fpage>20</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Клименко А.О., Синицын В.Е., Шрайнер И.В., Мершина Е.А., Лядов В.К., Петровичев В.С., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Клименко А.О., Синицын В.Е., Шрайнер И.В., Мершина Е.А., Лядов В.К., Петровичев В.С.</copyright-holder><copyright-holder xml:lang="en">Klimenko A.O., Sinitsyn V.E., Shrainer I.V., Mershina E.A., Lyadov V.K., Petrovichev V.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.radp.ru/jour/article/view/55">https://www.radp.ru/jour/article/view/55</self-uri><abstract><p>Целью данного исследования явилась оценка КТ-волюмометрии с точки зрения прогнозирования ответа на неоадъювантную химиотерапию при местно-распространенном раке желудка. Объем опухоли до и после химиотерапии измеряли с использованием специального программного обеспечения 3D (GE AW Volumeshare 5) и сравнивали с гистопатологической оценкой ответа. У пациентов с хорошим ответом средний объем опухоли уменьшался на 54 % против 21 % у пациентов с плохим ответом, р &lt; 0,0001. КТ волюметрия при сокращении объема опухоли в среднем на 37 % прогнозирует хороший морфологический ответ после 3 циклов неоадъювантной химиотерапии при локальном раке желудка с общей точностью 92 %.</p></abstract><trans-abstract xml:lang="en"><p>This study's aim is to evaluate the accuracy of CT volumetry in terms of predicting response to NAC in locally advanced GC. Pre- and post-chemotherapy volume of the tumor were measured using a dedicated 3D software (GE AW Volumeshare 5) and compared to histopathologic assessment of response. In patients with good response median tumor volume decrease was 54% vs 21% in patients with poor response, р &lt; 0,0001. CT volumetry with a cut-off 37 % of tumor volume reduction predicts good morphological response after 3 cycles oof neoadjuvant chemotherapy in locally advanced gastric cancer with an overall accuracy of 92 %.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>обзор</kwd><kwd>рак желудка</kwd><kwd>лучевая диагностика</kwd><kwd>компьютерная томография</kwd><kwd>волюметрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Review</kwd><kwd>Gastric Cancer</kwd><kwd>Radiologic Diagnosis</kwd><kwd>Computer Tomography</kwd><kwd>Volumetry</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Давыдов М. И., Туркин И. Н., Давыдов М. М. Энциклопедия хирургии рака желудка. М.: Эксмо, 2011. 532 с.</mixed-citation><mixed-citation xml:lang="en">Давыдов М. И., Туркин И. Н., Давыдов М. М. Энциклопедия хирургии рака желудка. 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