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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">radiology</journal-id><journal-title-group><journal-title xml:lang="ru">Радиология — практика</journal-title><trans-title-group xml:lang="en"><trans-title>Radiology - Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2713-0118</issn><publisher><publisher-name>Центральный научно-исследовательский институт лучевой диагностики</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">radiology-587</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ И КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS AND BRIEF REPORTS</subject></subj-group></article-categories><title-group><article-title>Томосинтез в диагностике рака молочной железы у пациентки с плотным рентгенологическим фоном (клинический пример)</article-title><trans-title-group xml:lang="en"><trans-title>Digital Breast Tomosynthesis in Breast Cancer Diagnosis of the Patient with Extremely Breast Density (The Clinical Example)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0635-4438</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasil'ev</surname><given-names>Aleksandr Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, член-корреспондент РАН</p></bio><bio xml:lang="en"><p>M. D. Med., Corresponding Member of the Russian Academy of Sciences</p></bio><email xlink:type="simple">auv62@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлова</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlova</surname><given-names>Tamara V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ГБУЗ «Московский клинический научный центр им. А. С. Логинова» Департамента здравоохранения г. Москвы</p></bio><bio xml:lang="en"><p>Ph. D. Med., Head of Department of Radiology № 2</p></bio><email xlink:type="simple">chaleur1891@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мануйлова</surname><given-names>О. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Manuylova</surname><given-names>Ol'ga O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-рентгенолог отделения лучевой диагностики № 2</p></bio><bio xml:lang="en"><p>Radiologist of Department of Radiology № 2</p></bio><email xlink:type="simple">moek@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Касаткина</surname><given-names>Л. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kasatkina</surname><given-names>Larisa I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заведующий онкологическим отделением № 2</p></bio><bio xml:lang="en"><p>Head of Department of Oncology № 2</p></bio><email xlink:type="simple">l2490193@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ротин</surname><given-names>Д. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Rotin</surname><given-names>Daniil L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, ведущий научный сотрудник лаборатории патоморфологии</p></bio><bio xml:lang="en"><p>M. D. Med., Leading Researcher of Laboratory of Pathomorphology</p></bio><email xlink:type="simple">d.rotin@mknc.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Еремеева</surname><given-names>Е. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Eremeeva</surname><given-names>Elizaveta R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>клинический ординатор кафедры патологической анатомии</p></bio><bio xml:lang="en"><p>Clinical Resident at the Department of Pathological Anatomy</p></bio><email xlink:type="simple">eremeevaelizaveta@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ООО «Центральный научно-исследова-&#13;
тельский институт лучевой диагностики»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Research Institute of Radiation Diagnostics</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ «Московский клинический научный центр им. А. С. Логинова» Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Clinical Research Center named after A. S. Loginov, Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ «Московский клинический научный центр им. А. С. Логинова» Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Clinical Research Center named after A. S. Loginov, Moscow Healthcare Department.</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>«Московский клинический научный центр им. А. С. Логинова» Департамента здравоохранения г. Москвы.</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Clinical Research Center named after A. S. Loginov, Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.Н. Евдокимова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State Medical University of Medicine and Dentistry named after A. I. Evdokimov, Ministry of Healthcare of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>24</day><month>02</month><year>2024</year></pub-date><volume>0</volume><issue>5</issue><fpage>38</fpage><lpage>44</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Васильев А., Павлова Т., Мануйлова О., Касаткина Л., Ротин Д., Еремеева Е., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Васильев А., Павлова Т., Мануйлова О., Касаткина Л., Ротин Д., Еремеева Е.</copyright-holder><copyright-holder xml:lang="en">Vasil'ev A., Pavlova T., Manuylova O., Kasatkina L., Rotin D., Eremeeva E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.radp.ru/jour/article/view/587">https://www.radp.ru/jour/article/view/587</self-uri><abstract><p>Представлен клинический пример, демонстрирующий диагностические возможности томосинтеза у пациентки с плотным рентгенологическим фоном молочных желез. По данным обзорной цифровой маммографии у пациентки отмечалась высокая рентгенологическая плотность молочных желез. В нижнем отделе левой молочной железы определялся участок очаговой асимметрии, категория BIRADS 3. Обследование было дополнено методикой томосинтеза, по данным которой в левой молочной железе визуализировалось узловое образование, имеющее признаки, характерные категории BI-RADS 5. Изменения в ткани левой молочной железы были подтверждены и при ультразвуковом исследовании, выполненном в B-режиме (BI-RADS 4). После чего была выполнена стереотаксическая трепанобиопсия измененного участка с последующей морфологической верификацией, по результатам которой у пациентки верифицирован рак молочной железы (BI-RADS 6).</p></abstract><trans-abstract xml:lang="en"><p>The clinical example demonstrating the diagnostic possibilities of digital breast tomosynthesis of the patient with dense breast is presented. According to the full-field digital mammography, the patient had an extremely dense breast. A region of focal asymmetry was determined in the lower part of the left breast, category BI-RADS 3. The examination was supplemented with the digital breast tomosynthesis technique, according to which the node with characteristic of BI-RADS 5 was visualized in the left breast. Changes in the left breast tissue have been confirmed by ultrasound examination in B-mode (BI-RADS 4). After that, a stereotaxic core biopsy of the abnormal area was performed, followed by morphological verification, according to which the patient was verified with breast cancer (BI-RADS 6).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>плотность ткани молочной железы</kwd><kwd>цифровая маммография</kwd><kwd>томосинтез</kwd><kwd>ультразвуковое исследование</kwd><kwd>кор-биопсия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Breast Cancer</kwd><kwd>Breast Density</kwd><kwd>Digital Mammography</kwd><kwd>Digital Breast Tomosynthesis</kwd><kwd>Ultrasound Examination</kwd><kwd>Breast Core Biopsy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Васильев А. Ю., Павлова Т. В., Касаткина Л. И., Мануйлова О. О., Ротин Д. Л. 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