<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">radiology</journal-id><journal-title-group><journal-title xml:lang="ru">Радиология — практика</journal-title><trans-title-group xml:lang="en"><trans-title>Radiology - Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2713-0118</issn><publisher><publisher-name>Центральный научно-исследовательский институт лучевой диагностики</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">radiology-83</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Диагностическая ценность кальциевого индекса при выполнении стандартной и низкодозовой компьютерной томографии органов грудной клетки без электрокардиографической синхронизации</article-title><trans-title-group xml:lang="en"><trans-title>Coronary Calcium Screening with Non-Gated Standard and Low-Dose Chest Computed Tomography in Comparison to Electrocardiographic-Gated Calcium Scoring</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1733-267X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Журавлев</surname><given-names>К. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhuravlev</surname><given-names>K. N.</given-names></name></name-alternatives><email xlink:type="simple">kir232@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5649-2193</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синицын</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinitsyn</surname><given-names>V. E.</given-names></name></name-alternatives><email xlink:type="simple">vsini@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ «Городская клиническая больница им. И.В. Давыдовского Департамента здравоохранения города Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I. V. Davidovsky Clinical Hospital, Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Московский государственный университет им. М. В. Ломоносова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Lomonosov Moscow State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>28</day><month>02</month><year>2020</year></pub-date><volume>0</volume><issue>1</issue><fpage>8</fpage><lpage>20</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Журавлев К.Н., Синицын В.Е., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Журавлев К.Н., Синицын В.Е.</copyright-holder><copyright-holder xml:lang="en">Zhuravlev K.N., Sinitsyn V.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.radp.ru/jour/article/view/83">https://www.radp.ru/jour/article/view/83</self-uri><abstract><p>Кальциноз коронарных артерий является характерным признаком коронарного атеросклероза, который часто выявляется на компьютерной томографии (КТ) органов грудной клетки. Целью этого исследования являлась оценка сопоставимости значений кальциевого индекса (КИ), рассчитанных по данным КТ органов грудной клетки без электрокардиографической (ЭКГ) синхронизации по сравнению с классической методикой КИ. 425 пациентам была выполнена КТ органов грудной клетки и КИ: 214 пациентам - по стандартному протоколу КТ, 211 пациентам - по низкодозному. Оценивались совпадения по абсолютным значениям КИ по Агатстону и по стратификации пациентов по 5 категориям риска. Корреляция между значениями КИ, полученными классическим методом, и по данным КТ органов грудной клетки оказалась достаточно высокой (r = 0,985). Она оставалась высокой даже после исключения из анализа значений КИ = 0 (r = 0,975). Степень совпадения по стратификации значений КИ по группам риска оказалась также достаточно высокой c коэффициентом сопряженности каппа k = 0,885. Исследование показало, что КИ может быть подсчитан по КТ органов грудной клетки с высокой степенью корреляции с классическим КИ как по абсолютным значениям, так и при стратификации по группам риска.</p></abstract><trans-abstract xml:lang="en"><p>Coronary artery calcification (CAC) is a recognized marker of coronary atherosclerosis. It is frequently detected on chest computed tomography (CT). The purpose of this study was to evaluate the correlation between the coronary calcium scoring values obtained with gated CT and with non-gated standard and low-dose chest CT. 425 consecutive patients prospectively studied with non-gated chest CT: 214 patients with the standard CT protocol and 211 patients with the low-dose one. Values of Agatston calcium score and stratification of patients into five calcium score risk categories were compared with the reference data from gated cardiac CT group. The correlation between CAC scores obtained with gated and non-gated CT was high (r = 0,977 for standard CT and 0,988 for low-dose CT). It remained high after exclusion from analysis the values of CAC score = 0 (r = 0,975 and 0,986, resp.). Categorization of patients into the five calcium score risk groups was also high for the both chest CT protocols (kappa 0,877 and 0,892, resp.). The study shows that analysis of CAC and the risk stratification of the screened patients is feasible with help of non-gated chest CT.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>кальциевый индекс</kwd><kwd>индекс коронарного кальция</kwd><kwd>кальциноз коронарных артерий</kwd><kwd>низкодозовая компьютерная томография</kwd><kwd>ишемическая болезнь сердца</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Calcium Score</kwd><kwd>Coronary Artery Calcification</kwd><kwd>Lung Cancer Screening</kwd><kwd>Low-Dose Computed Tomography</kwd><kwd>Coronary Artery Disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Agatston A. S., Janowitz W. R., Hildner F. J. et al. Quantification of coronary artery calcium using ultrafast computed tomography // J. Am. Coll. Cardiol. 1990. V. 15. № 4. P. 827-32.</mixed-citation><mixed-citation xml:lang="en">Agatston A. S., Janowitz W. R., Hildner F. J. et al. Quantification of coronary artery calcium using ultrafast computed tomography // J. Am. Coll. Cardiol. 1990. V. 15. № 4. P. 827-32.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Arcadi T., Maffei E., Sverzellati N. et al. Coronary artery calcium score on low-dose computed tomography for lung cancer screening // World. J. Radiol. 2014. V. 6. № 6. P.381-387.</mixed-citation><mixed-citation xml:lang="en">Arcadi T., Maffei E., Sverzellati N. et al. Coronary artery calcium score on low-dose computed tomography for lung cancer screening // World. J. Radiol. 2014. V. 6. № 6. P.381-387.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Benjamin E. J., Virani S. S., Callaway C. W. et al. Heart disease and stroke statistics: 2018 update - a report from the American heart association // Circ. 2018. V. 137. № 12. P. 67-492.</mixed-citation><mixed-citation xml:lang="en">Benjamin E. J., Virani S. S., Callaway C. W. et al. Heart disease and stroke statistics: 2018 update - a report from the American heart association // Circ. 2018. V. 137. № 12. P. 67-492.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Chiles C., Duan F., Gladish G. W. et al. Association of coronary artery calcification and mortality in the national lung screening trial: a comparison of three scoring methods // Radiol. 2015. V. 276. № 1. P. 82-90.</mixed-citation><mixed-citation xml:lang="en">Chiles C., Duan F., Gladish G. W. et al. Association of coronary artery calcification and mortality in the national lung screening trial: a comparison of three scoring methods // Radiol. 2015. V. 276. № 1. P. 82-90.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Detrano R., Guerci A. D., Carr J. J. et al. Coronary calcium as a predictor of coronary events in four racial or ethnic groups // N. Engl. J. Med. 2008. V. 358. № 13. P. 1336-45.</mixed-citation><mixed-citation xml:lang="en">Detrano R., Guerci A. D., Carr J. J. et al. Coronary calcium as a predictor of coronary events in four racial or ethnic groups // N. Engl. J. Med. 2008. V. 358. № 13. P. 1336-45.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Goff Jr. D. C., Lloyd-Jones D. M., Bennett G. et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk // J. Am. Coll. Cardiol. 2014. V. 63. № 25. Pt. B. P. 2935-2959.</mixed-citation><mixed-citation xml:lang="en">Goff Jr. D. C., Lloyd-Jones D. M., Bennett G. et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk // J. Am. Coll. Cardiol. 2014. V. 63. № 25. Pt. B. P. 2935-2959.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Greenland P., Blaha M. J., Budoff M. J. et al. Coronary calcium score and cardiovascular risk // J. Am. Coll. Cardiol. 2018. V. 72. № 4. P. 434-444.</mixed-citation><mixed-citation xml:lang="en">Greenland P., Blaha M. J., Budoff M. J. et al. Coronary calcium score and cardiovascular risk // J. Am. Coll. Cardiol. 2018. V. 72. № 4. P. 434-444.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Han D., Lee J. H., Hartaigh B. Ó., Min J. K. Role of computed tomography screening for detection of coronary artery disease // Clin. Imag. 2016. V. 40. № 2. P. 307- 310.</mixed-citation><mixed-citation xml:lang="en">Han D., Lee J. H., Hartaigh B. Ó., Min J. K. Role of computed tomography screening for detection of coronary artery disease // Clin. Imag. 2016. V. 40. № 2. P. 307- 310.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Hecht H. S., Cronin P., Blaha M. J. et al. 2016 SCCT/STR guidelines for coronary artery calcium scoring of noncontrast noncardiac chest CT scans: a report of the society of cardiovascular computed tomography and society of thoracic radiology // J. Thorac. Imag. 2017. V. 32. № 5. P. 54-66.</mixed-citation><mixed-citation xml:lang="en">Hecht H. S., Cronin P., Blaha M. J. et al. 2016 SCCT/STR guidelines for coronary artery calcium scoring of noncontrast noncardiac chest CT scans: a report of the society of cardiovascular computed tomography and society of thoracic radiology // J. Thorac. Imag. 2017. V. 32. № 5. P. 54-66.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Kim Y. K., Sung Y. M, Cho S. H. et al. Reliability analysis of visual ranking of coronary artery calcification on low-dose CT of the thorax for lung cancer screening: comparison with ECG-gated calcium scoring CT // Int. J. Cardiovasc. Imag. 2014. V. 30. Suppl. 2. P. 81-87.</mixed-citation><mixed-citation xml:lang="en">Kim Y. K., Sung Y. M, Cho S. H. et al. Reliability analysis of visual ranking of coronary artery calcification on low-dose CT of the thorax for lung cancer screening: comparison with ECG-gated calcium scoring CT // Int. J. Cardiovasc. Imag. 2014. V. 30. Suppl. 2. P. 81-87.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Piepoli M. F., Hoes A. W., Agewall S. et al. European guidelines on cardiovascular disease prevention in clinical practice // Eur. Heart. J. 2016. V. 37. № 29. P. 2315-2381.</mixed-citation><mixed-citation xml:lang="en">Piepoli M. F., Hoes A. W., Agewall S. et al. European guidelines on cardiovascular disease prevention in clinical practice // Eur. Heart. J. 2016. V. 37. № 29. P. 2315-2381.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Xie X., Zhao Y., de Bock G. H. et al. Validation and prognosis of coronary artery calcium scoring in nontriggered thoracic computed tomography // Circ. Cardiovasc. Imag. 2013. V. 6. № 4. P. 514-521.</mixed-citation><mixed-citation xml:lang="en">Xie X., Zhao Y., de Bock G. H. et al. Validation and prognosis of coronary artery calcium scoring in nontriggered thoracic computed tomography // Circ. Cardiovasc. Imag. 2013. V. 6. № 4. P. 514-521.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
