The Role of Perfusion Computed Tomography of the Liver in the Assessment of Hemodynamics in Patients with Compensated Cirrhosis of the Liver and the Presence of Type 2 Diabetes Mellitus. Pilot Study
https://doi.org/10.52560/2713-0118-2021-2-62-71
Abstract
Currently the relationship between liver diseases and glucose metabolism disorders is being studied. To characterize the negative impact of the mechanisms of insulin resistance on the liver parenchyma altered due to cirrhosis, we can use CT-perfusion of the liver — a method that allows us to assess hemodynamic disorders in the liver tissue. During the pilot study, it was found that the values of arterial perfusion and hepatic perfusion index in patients with compensated cirrhosis of the liver in the presence of type 2 diabetes mellitus were statistically significantly higher than in the absence of this pathology (p = 0,007 and p = 0,009 respectively). The values of portal and total perfusion in patients with compensated cirrhosis of the liver in the presence of type 2 diabetes mellitus were significantly lower than in the absence of this pathology (p < 0,001 and p = 0,007 respectively). CT-perfusion of the liver can be used in patients with compensated cirrhosis and the presence of type 2 diabetes mellitus in the anamnesis as a non-invasive method of instrumental diagnosis of hemodynamic changes, including in assessing the progression of portal hypertension and the subsequent detection of concomitant complications.
About the Authors
G. A. Stashuk
Moscow Regional Research and Clinical Institute
Russian Federation
Russian Federation
Stashuk Galina Aleksandrovna, M. D. Med., Head, Department of Roentgenology № 2; Professor, Chair of Radiation Diagnostics, Postgraduate Training Faculty
61/2, ul. Shchepkina, Moscow, 129110
Phone number: +7 (495) 684-57-09
Ya. G. Moisyuk
Moscow Regional Research and Clinical Institute
Russian Federation
Russian Federation
Moisyuk Yan Gennad’evich, M. D. Med., Professor, Head, Department of Transplantology
61/2, ul. Shchepkina, Moscow, 129110
Phone number: +7 (495) 681-35-09
D. Ya. Smirnova
Moscow Regional Research and Clinical Institute
Russian Federation
Russian Federation
Smirnova Dar’ya Yakovlevna, Postgraduate Student, Chair of Radiation Diagnostics
61/2, ul. Shchepkina, Moscow, 129110
Phone number: +7 (910) 002-28-75
O. V. Sumtsova
Moscow Regional Research and Clinical Institute
Russian Federation
Russian Federation
Sumtsova Ol’ga Vasil’evna, Junior Scientific Researcher, Department of Liver Surgery and Transplantation, Department of Transplantology
61/2, ul. Shchepkina, Moscow, 129110
Phone number: +7 (495) 681-35-09
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Review
For citations:
Stashuk G.A., Moisyuk Ya.G., Smirnova D.Ya., Sumtsova O.V. The Role of Perfusion Computed Tomography of the Liver in the Assessment of Hemodynamics in Patients with Compensated Cirrhosis of the Liver and the Presence of Type 2 Diabetes Mellitus. Pilot Study. Radiology - Practice. 2021;(2):62-71. (In Russ.) https://doi.org/10.52560/2713-0118-2021-2-62-71
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