MR morphometry in the diagnosis of MR-negative focal cortical dysplasia (clinical case)
A. M. Shevchenko,
E. L. Pogosbekyan,
P. A. Vlasov,
S. B. Agrba,
S. A. Galstyan,
A. I. Batalov,
A. G. Melikyan,
I. N. Pronin https://doi.org/10.52560/2713-0118-2024-1-104-114
Abstract
We presented a clinical case of MR-negative focal cortical dysplasia (FCD) type IIb, in which diagnostic value of semi- and automatic MR morphometry has been established. This method identified specific features for FCD in a patient with MR-negative form of focal epilepsy, such as blurring of the grey-white matter border and thickening of the cortex. The histological diagnosis of FCD type IIb has been confirmed in the region of interest detected by MR morphometry. Seizure freedom (Engel class Ia, follow-up 5 years) has been achieved after the surgical resection.
About the Authors
A. M. Shevchenko
Burdenko National Medical Research Center of Neurosurgery of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Shevchenko Alexander Mikhailovich, Doctor of Department of X-ray and Radioisotope Diagnostic Methods
16, ul. 4-ya Tverskaya-Yamskaya, Moscow, 125047
+7 (925) 488-83-60
E. L. Pogosbekyan
Burdenko National Medical Research Center of Neurosurgery of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Pogosbekyan Eduard Leonidovich, medical physicist of Department of X-ray and Radioisotope Diagnostic Methods
16, ul. 4-ya Tverskaya-Yamskaya, Moscow, 125047
+7 (925) 488-83-60
P. A. Vlasov
Burdenko National Medical Research Center of Neurosurgery of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Vlasov Pavel Alexandrovich, Doctor of the Second Neurosurgical Department of Federal State Autonomous Institution
16, ul. 4-ya Tverskaya-Yamskaya, Moscow, 125047
+7 (926) 586-47-23
S. B. Agrba
Burdenko National Medical Research Center of Neurosurgery of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Agrba Sariya Badrievna, Doctor of the Second Neurosurgical Department of Federal State Autonomous Institution
16, ul. 4-ya Tverskaya-Yamskaya, Moscow, 125047
+7 (901) 427-92-91
S. A. Galstyan
Burdenko National Medical Research Center of Neurosurgery of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Galstyan Syuzanna Andranikovna, pathologist of Federal State Autonomous Institution
16, ul. 4-ya Tverskaya-Yamskaya, Moscow, 125047
+7 (915) 002-76-36
A. I. Batalov
Burdenko National Medical Research Center of Neurosurgery of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Batalov Artem Igorevich, researcher of physicist of of Department of X-ray and Radioisotope Diagnostic Methods
16, ul. 4-ya Tverskaya-Yamskaya, Moscow, 125047
+7 (916) 066-20-50
A. G. Melikyan
Burdenko National Medical Research Center of Neurosurgery of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Melikyan Armenak Grigorievich, Doctor of Medical Sciences, Professor, Head of the Second Neurosurgical Department
16, ul. 4-ya Tverskaya-Yamskaya, Moscow, 125047
+7 499 972-85-55
I. N. Pronin
Burdenko National Medical Research Center of Neurosurgery of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Pronin Igor’ Nikolaevich, M. D. Med., Professor, Academician of the Russian Academy of Sciences, Head of Department of X-ray and Radioisotope Diagnostic Methods, N. N. Burdenko National Medical Research Center of Neurosurgery of the Ministry of Health of the Russian Federation
16, ul. Tverskaya-Yamskaya, Moscow, 125047
+7 499 972-85-55
References
1. Kuzniecky R. I. Magnetic resonance imaging in developmental disorders of the cerebral cortex. Epilepsia. 1994;35:S44- S56. DOI: 10.1111/j.1528-1157.1994.tb05988.x
2. Guerrini R., Sicca F., Parmeggiani L. Epilepsy and malformations of the cerebral cortex. Epileptic Disorders. 2003;5(2):9-26.
3. Schuele S. U., Lüders H. O. Intractable epilepsy: Management and therapeutic alternatives. Lancet Neurol. 2008;7:514- 524. DOI: 10.1016/S1474-4422(08)70108-X
4. Ganji Z., Hakak M. A., Zamanpour S. A., Zare H. Automatic Detection of Focal Cortical Dysplasia Type II in MRI: Is the Application of Surface-Based Morphometry and Machine Learning Promising? Front. Hum. Neurosci. 2021;19; 15:608285. DOI: 10.3389/fnhum.2021.608285. PMID: 33679343; PMCID: PM C7933541.
5. Shevchenko A. M., Pogosbekyan E. L., Batalov A. I., Shul’tz E. I., Tyurina A. N., Fadeeva L. M., Shevchenko M. V., Vlasov P. A., Zakharova N. E., Melikyan A. G., Pronin I. N. Automatic Algorithm of Magnetic Resonance Morphometry in the Diagnosis of Focal Cortical Dysplasia. Radiology — Practice. 2022;(1):63-76. (In Russ.) https://doi.org/10.52560/2713-0118-2022-1-63-76
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For citations:
Shevchenko A.M., Pogosbekyan E.L., Vlasov P.A., Agrba S.B., Galstyan S.A., Batalov A.I., Melikyan A.G., Pronin I.N. MR morphometry in the diagnosis of MR-negative focal cortical dysplasia (clinical case). Radiology - Practice. 2024;(1):104-114. (In Russ.) https://doi.org/10.52560/2713-0118-2024-1-104-114
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