Human Brain Functional Magnetic Resonance Imaging for Language Cortex Localization in Presurgical Brain Mapping. Case report

In neurosurgical practice of neurosurgery, a task-based functional magnetic resonance imaging (tb-fMRI) with motor and speech paradigms is a common method in preoperative planning lesion location around eloquent areas of the brain. This method can improve the surgical strategy with relevant information obtained non-invasively. But in majority of cases the results of tb-fMRI depend on the patient’s ability to follow instructions during study, which can be impaired due to brain tumor. When tasks cannot be performed by patient, the resting-state fMRI method (rs-fMRI) is more preferable. In this work, that is a part of the scientific project in assessment of neuronal activity in cases with brain gliomas of various localization, we present two cases of patients with glial tumors localized in the left hemisphere of the brain: frontal and temporal lobes with close proximity to Broca and Wernike areas. Based on a comparison of the results of tb-fMRT, rs-fMRT as well as direct cortical stimulation data, we propose a method for estimation the accuracy of coincidence in cortical activations obtained by three methods.

Brain Magnetic Resonance Imaging, Functional Magnetic Resonance Imaging, Resting-State Functional Magnetic Resonance Imaging, Presurgical Planning, Brain Mapping, Glioma, Eloquent Area

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