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The Difficulties of Diagnosing Tumor of the Ewing’s Family of Sarcomas in an Emergency Hospital (Clinical Observation)

https://doi.org/10.52560/2713-0118-2021-6-55-66

Abstract

The author presents his own clinical case demonstrating the long stage and difficulties in diagnosing a rare tumor of the Ewing’s Family of Sarcomas in a young patient, due to the peculiarity of the course of the disease, manifested by a non-pathognomonic clinical pattern.

About the Authors

A. Yu. Vasil’ev
Central Radiology Research Institute; Moscow State Medical University of Medicine and Dentistry named after A. I. Evdokimov
Russian Federation

Vasil’ev Aleksandr Yur’evich, M. D. Med., Corresponding Member of Russian Academy of Sciences, Head; Professor of Department of Radiology

9а, ul. Vucheticha, Moscow, 127206, Russia

Phone number: +7 (495) 611-01-77



T. V. Pavlova
Central Radiology Research Institute; City Clinical Hospital named after V. M. Buyanov, Department of Healthcare of Moscow
Russian Federation

Pavlova Tamara Valer’evna, Ph. D. Med., Senior Researcher; Radiologyst of Department of Radiation Diagnostic

26, ul. Bakinskaya, Moscow, 115516, Russia

Phone number: +7 (916) 483-14-92



V. A. Nechaev
City Clinical Hospital named after V. M. Buyanov, Department of Healthcare of Moscow
Russian Federation

Nechaev Valentin Aleksandrovich, Ph. D. Med., Radiologyst of Department of Radiation Diagnostic

26, ul. Bakinskaya, Moscow, 115516, Russia

Phone number: +7 (926) 575-36-16



Z. N. Baratashvili
City Clinical Hospital named after V. M. Buyanov, Department of Healthcare of Moscow
Russian Federation

Baramashvili Zurab Nodarievich, Ultrasound Specialist of Department of Radiation Diagnostic

26, ul. Bakinskaya, Moscow, 115516, Russia

Phone number: +7 (925) 305-27-24



O. O. Manuylova
Central Radiology Research Institute; City Clinical Hospital named after V. M. Buyanov, Department of Healthcare of Moscow
Russian Federation

Manuylova Olga Olegovna, Ph. D. Med., Senior Researcher; Chief of Department

26, ul. Bakinskaya, Moscow, 115516, Russia

Phone number: +7 (926) 220-37-25



References

1. Bilyalutdinova D. I., Kovalenko S. G., Spichak I. I. A clinical case of a tumor of the Ewing sarcoma family (a primitive neuroectodermal tumor) of rare localization in the parietal bone. Pediatric Bulletin of the Southern Urals. 2015. No. 2. P. 70–75 (in Russian).

2. Glekov I. V., Grigorenko V. A., Belova V. P., Yarkina A. V. Radiation therapy of tumors in children. Pediatrics. 2016. V. 3. No. 2. C. 143–144 (in Russian).

3. Evdokimova E. Yu., Zhestovskaya S. I., Potylitsyna E. A. Percutaneous biopsy under ultrasound control in the diagnosis of tumor diseases of the musculoskeletal system. Radiation diagnostics and therapy. 2017. V. 3. No. 8. P. 87–88 (in Russian).

4. Nisichenko O. A. Determination of the treatment strategy for localized and disseminated Ewing sarcomas in children and adolescents with primary pelvic bone damage: Dis. ... candidate of Medical Sciences. Moscow: National Medical Research Center of Oncology named after N. N. Blokhin, 2021. 132 p. (in Russian).

5. Samburova N. V., Pimenov I. A., Zhevak T. N., Litvitskiy P. F. Ewing’s sarcoma: molecular and genetic mechanisms of pathogenesis. Questions of modern pediatrics. 2019. V. 18. No. 4. C. 257–263 (in Russian). DOI: 10.15690/vsp.v18i4.2042.

6. Fedenko A. A., Bokhyan A. Yu., Gorbunova V. A., Makhson A. N., Teplyakov V. V. Practical recommendations for the drug treatment of primary malignant bone tumors (osteosarcomas, Ewing’s sarcomas). Malignant tumors. 2017. V. 7. No. 3S2. P. 203–215 (in Russian). DOI 10.18027/2224-5057-2017-7-3s2-203-215.

7. Khmelevskaya V. N., Kupriyanova E. I., Tsepenko V. V. Ewing’s sarcoma of the pelvic bones (Literary reference. A clinical case of long-term follow-up of a patient after the cure of Ewing’s sarcoma of pelvic bones with metastases to regional lymph nodes and to the right lung). Sarcomas of bones, soft tissues and skin tumors. 2019. V. 11. No. 1. P. 34–41 (in Russian).

8. Shalyga I. F., Achinovich S. L., Kozlovskaya T. V., Martem’yanova L. A., Turchenko S. Yu., Avizhets Yu. N. Ewing’s sarcoma. Problems of health and ecology. 2018. No. 1. P. 101–105 (in Russian).

9. Yurchenko D. Yu., Burtsev D. V., Kuznetsov S. A., Sagakyants A. B., Mkrtchyan G. A., Starzhetskaya M. V., Bespalova A. I., Popovyan O. P., Kushtova L. B. Some features of the molecular genetic pathogenesis of Ewing’s sarcoma. Modern problems of science and education. 2019. No. 3. P. 192 (in Russian).

10. Anderson M. E., Dubois S. G., Gebhart M. C. Chapter 89: Sarcomas of bone. In: Niederhuber J. E., Armitage J. O., Doroshow J. H., Kastan M. B., Tepper J. E., eds. Abeloff’s Clinical Oncology. 6th ed. Philadelphia, Pa: Elsevier; 2020.

11. Cash T., Mcllvaine E., Krailo M. D., Lessnick S. L., Lawlor E. R., Laack N., Sorger J., Marina N., Grier H. E., Granowetter L., Womer R. B., DuBois S. G. Comparison of clinical features and outcomes in patients with extraskeletal versus skeletal localized Ewing sarcoma: a report from the Children’s Oncology Group. Pediatr Blood Cancer. 2016; 63(10):1771–1779. DOI: 10.1002/pbc.26096.

12. Lin J. K., Liang J. Sinonasal Ewing sarcoma: a case report and literature review. Perm J. 2018; 22:17–086. DOI: 10.7812/ TPP/17-086


Supplementary files

1. КТ органов малого таза. Фрагмент видеопетли в аксиальной плоскости
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Type Исследовательские инструменты
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For citations:


Vasil’ev A.Yu., Pavlova T.V., Nechaev V.A., Baratashvili Z.N., Manuylova O.O. The Difficulties of Diagnosing Tumor of the Ewing’s Family of Sarcomas in an Emergency Hospital (Clinical Observation). Radiology - Practice. 2021;(6):55-66. (In Russ.) https://doi.org/10.52560/2713-0118-2021-6-55-66

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ISSN 2713-0118 (Online)