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Evaluation of the Efficacy of Neoadjuvant Radiation Twice a Day Fractionation Therapy in Patients with Resectable Pancreatic Head Cancer

https://doi.org/10.52560/2713-0118-2022-2-9-23

Abstract

The coronavirus of severe acute respiratory syndrome-2 (SARS-CoV-2) and the coronavirus infection caused by it, along with damage to the respiratory system, can lead to disorders of the central and peripheral nervous system. The article presents literature data and own observations of neurological disorders in patients with coronavirus disease in the superacute period. Pronounced neurological disorders are mainly observed in severe coronavirus disease and include acute ischemic stroke, subcortical micro- and macro— bleeding, acute necrotizing encephalopathy, Guillain-Barre syndrome. Factors potentially complicating the course of coronavirus disease and contributing to the development of neurological complications are hypertension, diabetes mellitus, chronic diseases of the heart and respiratory system. Based on existing publications and our own observations, we have systematized information about the relationship between coronavirus disease and neurological disorders, about possible factors contributing to the occurrence of stroke. The possibilities of using chest MSCT as the only method of radiation diagnostics for the early detection of viral pneumonia in patients receiving emergency and emergency care at the regional vascular center of BUZOO «GC BSMP No. 1» are considered. The use of this method, in the ultra-acute period of acute ischemic stroke, during the first 40 minutes from the moment of admission, can significantly reduce the time of diagnosis and mortality in patients with acute ischemic stroke and viral pneumonia.

About the Authors

L. I. Korytova
Russian Scientific Center of Radiology and Surgical Technologies named after Academician A.M. Granov of the Ministry of Health of the Russian Federation
Russian Federation

Luiza I. Korytova - М.D. Med., Professor, Honored Scientist of the Russian Federation, chief researcher of the Department of radiation and combined methods of treatment of the Academician A.M. Granov, Ministry  of Healthcare of Russia.

70, ul. Leningradskaja, p. Pesochnyj, St. Petersburg, 197758.

Phone number: 8 (921) 533-49-41



D. A. Sklyar
Russian Scientific Center of Radiology and Surgical Technologies named after Academician A.M. Granov of the Ministry of Health of the Russian Federation
Russian Federation

Dmitrij A. Sklyar - Specialist of the Department of Radiology, Surgery and Oncology   RSCRHT named after Academician A.M. Granov, Ministry of Healthcare of Russia.

70, ul. Leningradskaja, p. Pesochnyj, St. Petersburg, 197758.

Phone number: 8 (965) 062-22-01



E. V. Vlasova
Russian Scientific Center of Radiology and Surgical Technologies named after Academician A.M. Granov of the Ministry of Health of the Russian Federation
Russian Federation

Ekaterina V. Vlasova  - Radiation Oncologist of the Department of Radiotherapy No. 1 of the Academician A.M. Granov, Ministry of Healthcare of Russia.

70, ul. Leningradskaja, p. Pesochnyj, St. Petersburg, 197758.

Phone number: 8 (931) 342-41-52



A. V. Pavlovskiy
Russian Scientific Center of Radiology and Surgical Technologies named after Academician A.M. Granov of the Ministry of Health of the Russian Federation
Russian Federation

Aleksandr V. Pavlovskiy - М.D. Med., RSCRHT named after Academician A.M. Granov, Ministry of Healthcare of Russia.

70, ul.  Leningradskaja, p. Pesochnyj, St. Petersburg, 197758.

Phone number: 8 (921) 318-22-07



A. A. Polikarpov
Russian Scientific Center of Radiology and Surgical Technologies named after Academician A.M. Granov of the Ministry of Health of the Russian Federation
Russian Federation

Aleksey A. Polikarpov - М.D. Med., Professor of the Department of Radiology, Surgery and Oncology, Academician A.M. Granov, Ministry of Healthcare of Russia.

70, ul. Leningradskaja, p. Pesochnyj, St. Petersburg, 197758.

Phone number: 8 (921) 947-54-18



E. V. Moiseenko
Russian Scientific Center of Radiology and Surgical Technologies named after Academician A.M. Granov of the Ministry of Health of the Russian Federation
Russian Federation

Vladislav E. Moiseenko - Ph.D. Med., Surgeon of the Department of Surgery No. 2 of the Academician A.M. Granov, Ministry of Healthcare of Russia.

70, ul. Leningradskaja, p. Pesochnyj, St. Petersburg, 197758.

Phone number: 8 (911) 243-94-95



O. V. Korytov
Russian Scientific Center of Radiology and Surgical Technologies named after Academician A.M. Granov of the Ministry of Health of the Russian Federation
Russian Federation

Oleg V. Korytov - Ph.D. Med., radiation oncologist of the Department of Radiotherapy No. 3.

70, ul. Leningradskaja, p. Pesochnyj, St. Petersburg, 197758.

Phone number: 8 (921)939-13-16



References

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Review

For citations:


Korytova L.I., Sklyar D.A., Vlasova E.V., Pavlovskiy A.V., Polikarpov A.A., Moiseenko E.V., Korytov O.V. Evaluation of the Efficacy of Neoadjuvant Radiation Twice a Day Fractionation Therapy in Patients with Resectable Pancreatic Head Cancer. Radiology - Practice. 2022;(2):9-23. (In Russ.) https://doi.org/10.52560/2713-0118-2022-2-9-23

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ISSN 2713-0118 (Online)