Diagnosis and Treatment of Recurrent Malignant Peripheral Nerve Sheath Tumor (Literature Review and Clinical Case)
Abstract
Malignant peripheral nerve sheath tumors (MPNST) are rare soft tissue sarcomas with high potential to local recurrence and distant metastases. Intratoracic localization of primary MPNST is uncommon. Peritoneal involvement for extraabdominal MPNST is unusual. In our paper we would like to present a case of diagnosis and treatment of recurrent lung malignant peripheral nerve sheath tumor with diaphragmal pleura, lung and peritoneum involvement one year after atypical lung resection in 38-year-old patient.
About the Authors
Andrey D. Kaprin
National Medical Radiological Research Center, Ministry of Healthcare of Russia
Russian Federation
Russian Federation
- D. Med., Professor, Full Member of the Russian Academy of Sciences, Сorresponding member of Russian Academy of Education, Honored Doctor of the Russian Federation, Chief Urologist of the Russian Academy of Sciences, General Director of National Medical Radiological Research Center; Head of Department of Urology and Surgical Nephrology with a Course of Oncourology at the Medical Faculty of Medical Institute of the Peoples' Friendship University of Russia
Natalia A. Rubtsova
Moscow Research Oncology Institute named after P. A. Herzen – branch of National Medical Research Radiological Center, Ministry of Healthcare of Russia
Russian Federation
Russian Federation
M. D. Med., Head of Department of Radiology
Alexandr I. Khalimon
Moscow Research Oncology Institute named after P. A. Herzen – branch of National Medical Research Radiological Center, Ministry of Healthcare of Russia
Russian Federation
Russian Federation
Radiologist of Department of Radiology
Antonina V. Levshakova
Moscow Research Oncology Institute named after P. A. Herzen – branch of National Medical Research Radiological Center, Ministry of Healthcare of Russia
Russian Federation
Russian Federation
M. D. Med., Senior Researcher of Radiology of Department
Andrey B. Ryabov
Moscow Research Oncology Institute named after P. A. Herzen – branch of National Medical Research Radiological Center, Ministry of Healthcare of Russia
Russian Federation
Russian Federation
M. D. Med., Head of Thoracoabdominal Oncosurgery Division
Oleg V. Pikin
Moscow Research Oncology Institute named after P. A. Herzen – branch of National Medical Research Radiological Center, Ministry of Healthcare of Russia
Russian Federation
Russian Federation
M. D. Med., Professor, Head of Thoracic Surgery Department
Ali M. Amiraliev
Moscow Research Oncology Institute named after P. A. Herzen – branch of National Medical Research Radiological Center, Ministry of Healthcare of Russia
Russian Federation
Russian Federation
Ph. D. Med., Researcher of Thoracic Surgery Department
Nadezhda N. Volchenko
Moscow Research Oncology Institute named after P. A. Herzen – branch of National Medical Research Radiological Center, Ministry of Healthcare of Russia
Russian Federation
Russian Federation
M. D. Med., Professor, Head of Oncomorphology of Department
Anna B. Bruslinskaya
Moscow Research Oncology Institute named after P. A. Herzen – branch of National Medical Research Radiological Center, Ministry of Healthcare of Russia
Russian Federation
Russian Federation
Pathologist of Department of Pathology
References
1. Weiss S. W., Goldblum J. R. Enzinger and Weiss's Soft Tissue Tumors. 6th Edition // Elsevier Health Sciences. Philadelphia, 2013.
2. Sperandio M., Di Poce I., Ricci A. et al. Malignant peripheral nerve sheath tumour: CT and MRI Findings // Case Rep. Radiol. 2013. V. 2013.
3. Shyama P. S., Gangothri S., Reddy K. S. et al. Malignant peripheral nerve sheath tumor of the mandible: A case report and review of literature // J. Neurol. Res. 2011. V. 1. P. 219–222.
4. Guo A., Liu A., Wei L. et al. Malignant peripheral nerve sheath tumors: Differentiation patterns and immunohistochemical features — A mini-review and our new findings // J. Cancer. 2012. V. 3. P. 303–309.
5. Kolarov V., Stanic J., Eri Z. et al. Intrathoracic malignant peripheral nerve sheath tumor with poor outcome: a case report //Bosn. J. Basic Med. Sci. 2010. V. 10. № 4. P. 328–330.
6. La Mantia E., Franco R., Cantile M. et al. Primary intrapulmonary malignant peripheral nerve sheath tumor mimicking lung cancer // J. Thorac Dis. 2013. V. 5. № 4. P. 155–157.
7. Ralli M., Singh S., Hasija S. et al. Intrathoracic malignant peripheral nerve sheath tumor: histopathological and immunohistochemical features // Iran. J. Pathol. 2015. V. 10. № 1. P. 74–78.
8. Kroep J. R., Ouali M., Gelderblom H. et al. First-line chemotherapy for malignant peripheral nerve sheath tumor (MPNST) versus other histological soft tissue sarcoma subtypes and as a prognostic factor for MPNST: An EORTC Soft Tissue and Bone Sarcoma Group study // Ann. Oncol. 2011. V. 22. P. 207–214.
9. Gryglicka B., Szkutnik I. W., Milanowski J. Malignant peripheral nerve sheath tumor associated with clear cell carcinoma — case report // Pneumonol. Algerol. Pol. 2012. V. 80. № 3. P. 269–274.
10. Fletcher C. D. M., Bridge J. A., Hogendoorn P., Mertens F. WHO Classification of Tumours of Soft Tissue and Bone. Lyon, 2013. P. 14.
11. Benz M. R., Czernin J., Dry S. M. Quantitative F18-fluorodeoxyglucose positron emission tomography accurately characterizes peripheral nerve sheath tumors as malignant or benign // Cancer. 2010. V. 116. № 2. P. 451–458.
Review
For citations:
Kaprin A., Rubtsova N., Khalimon A., Levshakova A., Ryabov A., Pikin O., Amiraliev A., Volchenko N., Bruslinskaya A. Diagnosis and Treatment of Recurrent Malignant Peripheral Nerve Sheath Tumor (Literature Review and Clinical Case). Radiology - Practice. 2017;(3):29-38. (In Russ.)
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