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High-dose Rate Interstitial Brachytherapy in the Treatment of Locally Advanced Malignant Tumors of the Tongue

Abstract

The article presents the results of the use of interstitial HDR brachytherapy as a component in the complex therapy for tongue cancer. In the period from November 2013 to may 2015 treated 7 patients diagnosed with locally spread cancer of the tongue. In 6 cases HDR brachytherapy were used in combination with external beam therapy and only 1 patient we used this method in independent form. As a result of the treatment 3 patients had a complete clinical remission, confirmed by MRI data and histological examination (follow-up period lasted 2–18 months). The recurrence of the tongue cancer with metastases in the lymph nodes of the neck was diagnosed in 1 patient (4 months after the end of treatment). In 3 patients during follow-up revealed recurrence in the lymph nodes of the neck.

About the Authors

Arman M. Zhumankulov
SaintPetersburg City Clinical Oncology Dispensary, Ministry of Healthcare of Russia
Russian Federation

Oncologist



Tatyana V. Ostrinskaya
Saint Petersburg City Clinical Oncology Dispensary, Ministry of Healthcare of Russia
Russian Federation

Ph. D. M., Oncologist



Andrey P. Litvinov
Radiology Clinic of the Pavlov First St. Petersburg State Medical University, Ministry of Healthcare of Russia
Russian Federation

radiologist, head of Department



Andrei I. Yaremenko
Clinic of Maxillofacial Surgery; Pavlov First St. Petersburg State Medical University, Ministry of Healthcare of Russia
Russian Federation

M. D. Med., Head of Department of Surgical Dentistry and Maxillofacial Surgery, Head of Department of the Clinic of Maxillofacial Surgery; Vice-rector on Scientific Work of the Pavlov First St. Petersburg State Medical University



Georgy M. Manikhas
Saint Petersburg City Clinical Oncology Dispensary, Ministry of Healthcare of Russia
Russian Federation

honoured doctor of the Russian Federation, Corresponding Member of RANS, M. D, Med., Professor, Head of Department of Oncology



Zhanna S. Lebedevа
Clinic of Pavlov First St. Petersburg State Medical University, Ministry of Healthcare of Russia
Russian Federation

Health Physicist of Radiological Department



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Review

For citations:


Zhumankulov A., Ostrinskaya T., Litvinov A., Yaremenko A., Manikhas G., Lebedevа Zh. High-dose Rate Interstitial Brachytherapy in the Treatment of Locally Advanced Malignant Tumors of the Tongue. Radiology - Practice. 2016;(1):32-41. (In Russ.)

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ISSN 2713-0118 (Online)