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Coronary Calcium Score as Powerful Screening Method for Cardiovasculsr Diseases (Literature Review)

Abstract

Calcification of the coronary arteries is a quite common characteristic finding at chest CT, especially in elderly and smoking patients . The standardised method of evaluation of coronary artery calcification is a calcium score. Coronary calcium, quantified on ECG-gated CT examinations, is the strong predictor of cardiovascular events in the asymptomatic population. A zero calcium score stands alone as perhaps the most powerful «negative risk factor» for near-term development of a coronary event, particularly in patients with an intermediate-risk. According to international guidelines, the calcium score should be used in patients with intermediate risk or low risk with a cardiovascular family history. On the other hand, most of these patients may be candidates for lung cancer screening chest CTs, especially old patients and heavy smokers. The possibility of using standard and low-dose protocols of chest CTs in determining the calcium score is quite promising.

About the Authors

K. N. Zhuravlev
I. V. Davidovsky Clinical Hospital, Moscow
Russian Federation


V. E. Sinitsyn
ФГБОУ ВО «Московский государственный университет им. М.В. Ломоносова»
Russian Federation


A. V. Shpektor
Moscow State University of Medicine and Dentistry named after A. I. Evdokimov, Ministry of Healthcare of Russia
Russian Federation


References

1. Agatston A. S., Janowitz W. R., Hildner F. J. et al. Quantification of coronary artery calcium using ultrafast computed tomography // J. Am. Coll. Cardiol. 1990. V. 15. № 4. P. 827-832.

2. Benjamin E. J., Virani S. S., Callaway C. W. et al. Heart disease and stroke statistics: 2018 update - a report from the american heart association // Circ. 2018. V.137. № 12. P.67-49.

3. Detrano R., Guerci A. D., Carr J. J. et al. Coronary calcium as a predictor of coronary events in four racial or ethnic groups // N. Engl. J. Med. 2008. V. 358. № 13. P. 1336-1345.

4. Goff Jr. D. C., Lloyd-Jones D. M., Bennett G. et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk // J. Am. Coll. Cardiol. 2014. V. 63. № 25. Pt. B. P. 2935-2959.

5. Greenland P., Blaha M. J., Budoff M. J. et al. Coronary calcium score and cardiovascular risk // J. Am. Coll. Cardiol. 2018. V. 72. № 4. P. 434-444.

6. Han D., Lee J. H., Hartaigh B. Ó., Min J. K. Role of computed tomography screening for detection of coronary artery disease // Clin. Imag. 2016. V.40. № 2. P. 307-10.

7. Hecht H. S., Cronin P., Blaha M. J. et al. 2016 SCCT/STR guidelines for coronary artery calcium scoring of noncontrast noncardiac chest CT scans: A report of the society of cardiovascular computed tomography and society of thoracic radiology // J. Thorac. Imaging. 2017. V. 32. № 5. P.54-66.

8. Hutt A., Duhamel A., Deken V. et al. Coronary calcium screening with dual-source CT: reliability of ungated, high-pitch chest CT in comparison with dedicated calcium-scoring CT // Eur. Radiol. 2016. V. 26. № 6. P. 1521-8.

9. Liu W., Zhang Y., Yu C.-M. et al. Current understanding of coronary artery calcification // J. Geriatr. Cardiol. 2015. V. 12. № 6. P. 668-675.

10. Otsuka F., Sakakura K., Yahagi K., Joner M., Virmani R. Has our understanding of calcification in human coronary atherosclerosis progressed? // Arterioscler Thromb. Vasc. Biol. 2014. V. 34. № 4. P. 724-736.

11. Pencina M. J., Navar-Boggan A. M., D'Agostino R. B. et al. Application of new cholesterol guidelines to a population-based sample // NEngl. J. Med. 2014. V. 370. № 15. P. 1422-1431.

12. Piepoli M. F., Hoes A. W., Agewall S. et al. European guidelines on cardiovascular disease prevention in clinical practice // Eur. Heart. J. 2016. V. 37. № 29. P. 2315-2381.

13. Pursnani A., Massaro J. M., D'Agostino R. B. et al. Guideline-based statin eligibility, coronary artery calcification, and cardiovascular events // JAMA. 2015. V. 314. № 2. P. 134-4.

14. Sandfort V., Bluemke D. A. CT calcium scoring. History, current status and outlook // Diagn. Interv. Imag. 2017. V. 98. № 1. P. 3-10.

15. Shemesh J. Coronary artery calcification in clinical practice: what we have learned and why should it routinely be reported on chest CT? // Ann. Transl. Med. 2016. V. 4. № 8. P. 159.

16. Stone N. J., Robinson J., Lichtenstein A. H. et al. American college of cardiology/american heart association task force on practice guidelines. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American сollege of сardiology/American heart association task force on practice guidelines // J. Am. Coll. Cardiol. 2014. V. 63. № 25. Pt. B. P. 2889-2934.

17. Taïbi F., Metzinger-Le Meuth V., Massy Z. A., Metzinger L. MiR-223: An inflammatory oncomiR enters the cardiovascular field // Biochim. Biophys. Acta. 2014. V. 1842. № 7. P. 1001-1009.

18. Xie X., Zhao Y., de Bock G. H. et al. Validation and prognosis of coronary artery calcium scoring in nontriggered thoracic computed tomography // Circ. Cardiovasc. Imag. 2013. V. 6. № 4. P. 514-521.


Review

For citations:


Zhuravlev K.N., Sinitsyn V.E., Shpektor A.V. Coronary Calcium Score as Powerful Screening Method for Cardiovasculsr Diseases (Literature Review). Radiology - Practice. 2019;(6):60-72. (In Russ.)

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ISSN 2713-0118 (Online)