Preview

Radiology - Practice

Advanced search

Lymphoscintigraphy in the Diagnosis of а Sentinel Lymph Node in Patient with Malignant Oral Mucosa Before Biopsy. Clinical Observation

https://doi.org/10.52560/2713-0118-2026-2-88-97

Abstract

Objective. Regarding the role of lymphoscintigraphy in the diagnosis of sentinel lymph node in a patient with malignant lesions, an oral cavity examination is performed as a result of clinical observation.

Materials and Methods. The examination results and sentinel lymph node biopsy results are presented in a patient with T1N0M0 squamous cell carcinoma of the oral cavity, identified during intraoperative detection based on the results of indirect lymphoscintigraphy, supplemented by single-photon emission computed tomography with computed tomography (SPECT/CT).

Results. On the day of the surgical intervention, a lymphoscintigraphy was performed, during which the injection sites of the RFP were visualized, as well as the foci of hyperfixation located in the area of regional metastasis. These foci were located in the projection of the upper and middle jugular groups of the lymph nodes of the neck. During the surgical intervention, using a gamma detector, lymph nodes with an unchanged structure, but actively accumulating RFP, were identified. According to the results of the biopsy, malignant lesions of these lymph nodes were identified, which influenced the determination of the volume of lymphodissection.

Conclusion. Determining the exact location of a sentinel lymph node with a visually unchanged structure is an important step in staging malignant diseases, which will affect the patient's management.

About the Authors

A. A. Samodelkina
Research Institute of Clinical Oncology «Nizhny Novgorod Regional Clinical Oncological Dispensary»
Russian Federation

Samodelkina Anastasia Aleksandrovna, Radiologist, Department of the Radionuclide Diagnostics

Nizhny Novgorod



E. B. Petrova
Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical University» of the Ministry of Health of the Russian Federation
Russian Federation

Petrova Ekaterina Borisovna, D. Med., Associate Professor, Professor of the Department of Radiology, Faculty of Doctors Advanced Training

Nizhny Novgorod



S. P. Dmitriev
Research Institute of Clinical Oncology «Nizhny Novgorod Regional Clinical Oncological Dispensary»
Russian Federation

Dmitriev Sergey Pavlovich, Head of the 9th Oncology Department of Head and Neck Tumors

Nizhny Novgorod



T. V. Burova
Research Institute of Clinical Oncology «Nizhny Novgorod Regional Clinical Oncological Dispensary»
Russian Federation

Burova Tatyana Valer’evna, head of the Radionuclide Diagnostics Department

Nizhny Novgorod



S. V. Gamayunov
Research Institute of Clinical Oncology «Nizhny Novgorod Regional Clinical Oncological Dispensary»; Privolzhsky Research Medical University of the Ministry of Health of the Russia
Russian Federation

Gamayunov Sergey Viktorovich, MD, DSc, Chief Physician, Research Institute of Clinical Oncology «Nizhny Novgorod Regional Clinical Oncological Dispensary»; Professor, Prof. N. E. Yakhontov Department of Oncology, Radiation Therapy and Diagnostic Imaging, Privolzhsky Research Medical University of the Ministry of Health of the Russia

Nizhny Novgorod



References

1. Gelfand I. M., Kropotov M. A., Isaeva M. T., Podvyaznikov S. O. The importance in clinical practice of the signal lymph node biopsy in squamous cell carcinoma of the head and neck. Head and Neck Tumors. 2023;13(4):116-123. (In Russ.).

2. Dmitriev S. P., Ter-Ovanesov M. D., Kazakov A. A., Burova T. V., Aleksina V. I., Maslov N. M. Sentinel lymph node biopsy in head and neck tumors: current status from the standpoint of evidence-based medicine. The role of radioisotope diagnostics (literature review). Russian Surgical Journal. 2025;1(2):112-117. (In Russ.).

3. Margolin G., Mudunov A. M., Gelfand I. M., Alymov Yu. V., Akhundov A. A., Podvyaznikov S. O., Narimanov M. N., Zabotina T. N., Zakharova E. N. The need and advantages of personalized cervical lymph node dissection for cancer of the oral mucosa T1–2N0M0. The path to radical surgery. Head and Neck Tumors. 2018;8(4):26-31. (In Russ.).

4. Musin Sh. I., Osokin S. V., Yatsenko T. G., Sultanbaev A. V., Zamilov M. M., Vakhitov M. M., Ilyin V. V. Sentinel lymph node biopsy using the indirect lymphoscintigraphic method in cT1–2N0M0 oral mucosal cancer: results of a singlecenter study. Head and Neck Tumors. 2019;9(1):68-73. (In Russ.).

5. Sevryukov F. E., Polkin V. V., Panaseikin Yu. A., Sigov M. A., Zibirov R. F., Bekhtereva I. A., Ivanov S. A., Kaprin A. D. Sentinel lymph node biopsy experience in squamous cell carcinoma of the oral mucosa cT1–2N0M0. Head and Neck Tumors. 2023;13(4):37-47. (In Russ.).

6. Iimura T., Fukushima Y., Kumita S., Ogawa R., Hyakusoku H. Estimating lymphodynamic conditions and lymphovenous anastomosis efficacy using 99mTc-phytate lymphoscintigraphy with SPECT-CT in patients with lower-limb lymphedema. Plast. Reconstr. Surg. Glob. Open. 2015; 3(5):e404.

7. Ettinger D. S., Wood D. E., Aisner D. L., Akerley W., Bauman J. R., Bharat A., Bruno D. S., Chang J. Y., Chirieac L. R., D'Amico T. A., DeCamp M., Dilling T. J., Dowell J., Gettinger S., Grotz T. E., Gubens M. A., Hegde A., Lackner R. P., Lanuti M., Lin J., Loo B. W., Lovly C. M., Maldonado F., Massarelli E., Morgensztern D., Ng T., Otterson G. A., Pacheco J. M., Patel S. P., Riely G. J., Riess J., Schild S. E., Shapiro T. A., Singh A. P., Stevenson J., Tam A., Tanvetyanon T., Yanagawa J., Yang S. C., Yau E., Gregory K., Hughes M. Non-Small Cell Lung Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology. 2024;22(4):249-274.

8. Villa G., Campisi C. C., Ryan M., Boccardo F., Di Summa P., Frascio M., Sambuceti G., Campisi C. Procedural Recommendations for Lymphoscintigraphy in the Diagnosis of Peripheral Lymphedema: the Genoa Protocol. Nucl. Med. Mol. Imaging. 2019; 53(1):47-56.


Review

For citations:


Samodelkina A.A., Petrova E.B., Dmitriev S.P., Burova T.V., Gamayunov S.V. Lymphoscintigraphy in the Diagnosis of а Sentinel Lymph Node in Patient with Malignant Oral Mucosa Before Biopsy. Clinical Observation. Radiology - Practice. 2026;(2):88-97. (In Russ.) https://doi.org/10.52560/2713-0118-2026-2-88-97

Views: 153

JATS XML


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2713-0118 (Online)