Preview

Radiology - Practice

Advanced search

Coronary Calcium Screening with Non-Gated Standard and Low-Dose Chest Computed Tomography in Comparison to Electrocardiographic-Gated Calcium Scoring

Abstract

Coronary artery calcification (CAC) is a recognized marker of coronary atherosclerosis. It is frequently detected on chest computed tomography (CT). The purpose of this study was to evaluate the correlation between the coronary calcium scoring values obtained with gated CT and with non-gated standard and low-dose chest CT. 425 consecutive patients prospectively studied with non-gated chest CT: 214 patients with the standard CT protocol and 211 patients with the low-dose one. Values of Agatston calcium score and stratification of patients into five calcium score risk categories were compared with the reference data from gated cardiac CT group. The correlation between CAC scores obtained with gated and non-gated CT was high (r = 0,977 for standard CT and 0,988 for low-dose CT). It remained high after exclusion from analysis the values of CAC score = 0 (r = 0,975 and 0,986, resp.). Categorization of patients into the five calcium score risk groups was also high for the both chest CT protocols (kappa 0,877 and 0,892, resp.). The study shows that analysis of CAC and the risk stratification of the screened patients is feasible with help of non-gated chest CT.

About the Authors

K. N. Zhuravlev
I. V. Davidovsky Clinical Hospital, Moscow Healthcare Department
Russian Federation


V. E. Sinitsyn
Lomonosov Moscow State University
Russian Federation


References

1. Agatston A. S., Janowitz W. R., Hildner F. J. et al. Quantification of coronary artery calcium using ultrafast computed tomography // J. Am. Coll. Cardiol. 1990. V. 15. № 4. P. 827-32.

2. Arcadi T., Maffei E., Sverzellati N. et al. Coronary artery calcium score on low-dose computed tomography for lung cancer screening // World. J. Radiol. 2014. V. 6. № 6. P.381-387.

3. Benjamin E. J., Virani S. S., Callaway C. W. et al. Heart disease and stroke statistics: 2018 update - a report from the American heart association // Circ. 2018. V. 137. № 12. P. 67-492.

4. Chiles C., Duan F., Gladish G. W. et al. Association of coronary artery calcification and mortality in the national lung screening trial: a comparison of three scoring methods // Radiol. 2015. V. 276. № 1. P. 82-90.

5. Detrano R., Guerci A. D., Carr J. J. et al. Coronary calcium as a predictor of coronary events in four racial or ethnic groups // N. Engl. J. Med. 2008. V. 358. № 13. P. 1336-45.

6. Goff Jr. D. C., Lloyd-Jones D. M., Bennett G. et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk // J. Am. Coll. Cardiol. 2014. V. 63. № 25. Pt. B. P. 2935-2959.

7. Greenland P., Blaha M. J., Budoff M. J. et al. Coronary calcium score and cardiovascular risk // J. Am. Coll. Cardiol. 2018. V. 72. № 4. P. 434-444.

8. Han D., Lee J. H., Hartaigh B. Ó., Min J. K. Role of computed tomography screening for detection of coronary artery disease // Clin. Imag. 2016. V. 40. № 2. P. 307- 310.

9. Hecht H. S., Cronin P., Blaha M. J. et al. 2016 SCCT/STR guidelines for coronary artery calcium scoring of noncontrast noncardiac chest CT scans: a report of the society of cardiovascular computed tomography and society of thoracic radiology // J. Thorac. Imag. 2017. V. 32. № 5. P. 54-66.

10. Kim Y. K., Sung Y. M, Cho S. H. et al. Reliability analysis of visual ranking of coronary artery calcification on low-dose CT of the thorax for lung cancer screening: comparison with ECG-gated calcium scoring CT // Int. J. Cardiovasc. Imag. 2014. V. 30. Suppl. 2. P. 81-87.

11. Piepoli M. F., Hoes A. W., Agewall S. et al. European guidelines on cardiovascular disease prevention in clinical practice // Eur. Heart. J. 2016. V. 37. № 29. P. 2315-2381.

12. Xie X., Zhao Y., de Bock G. H. et al. Validation and prognosis of coronary artery calcium scoring in nontriggered thoracic computed tomography // Circ. Cardiovasc. Imag. 2013. V. 6. № 4. P. 514-521.


Review

For citations:


Zhuravlev K.N., Sinitsyn V.E. Coronary Calcium Screening with Non-Gated Standard and Low-Dose Chest Computed Tomography in Comparison to Electrocardiographic-Gated Calcium Scoring. Radiology - Practice. 2020;(1):8-20. (In Russ.)

Views: 421


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2713-0118 (Online)