A Comparative Analysis of the Results of Breast MRI and Large Section Histology in Preoperative Evaluation of the Breast Cancer Extent

The aim of the study was to assess the sensitivity of MRI in preoperative measurement of the extent of breast cancer (BC), determine the presence or absence of correlation with standard and postoperative large-section histological examination. 169 patients were divided into 2 groups according to the modern X-ray classification L. Tabar. All patients underwent a core biopsy with subsequent histological examination. The first group consisted of 57 (33,7 %) women with tumors arising in the terminal ductal-lobular unit -acinar adenocarcinoma (AAB) unifocal and multifocal forms, and the second group - 112 (66,3 %) women with types of ductal adenocarcinoma in situ (in situ/DAB) and ductal adenocarcinoma in situ associated with the acinar form of breast cancer (AAB - DAB). Pathologic findings on mammography were assessed using the modern classification of L. Tabar. Standard and large section histology were used after surgery. The results of tumor size evaluation according to the large-section histological examination and MRI of the breast in women with breast cancer originating in the main duct (DAB) were characterized by good comparability. Estimates of the size of the tumor of acinar origin, both unifocal and multifocal forms, obtained with the standard histological examination, were significantly lower (81,8 % of cases). Extent of breast cancer originating in the main ducts preoperatively measured by breast MRI correlates with data from a large-section histology study. Large-section histology allows to more accurately assess the correlation of histological and diagnostic methods, reducing the number of repeated surgical interventions.

Ductal Adenocarcinoma in Situ, Large Section Histology, Contrast-Enhanced Magnetic Resonance Imaging of the Breast

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