Material research are archived data in the Chelyabinsk Cancer Center for treatment of 42 patients who subsequently after chemoradiotherapy first tumor appeared metachronous multiple primary tumors. The average age of patients at diagnosis of the first tumor was 51,5 years (range 21 to 90 years; 95 % DI 47,79–55,21); the time interval between the first appearance of the tumor before the second tumor was on average 59,02 months (range 12 to 207 months; 95 % DI 45,17–72,87); the time interval from the beginning of first the chemotherapy until the second tumor tumors averaged 56,37 months (range 1 to 207 months; 95 % DI 43,18–69,56); the time interval from the beginning of first the radiotherapy until the second tumor tumors averaged 55,38 months (range 1 to 207 months; 95 % DI 42,08–68,41). On average, patients who received chemoradiotherapy first tumor, patients lived 91,90 months from the date of diagnosis of the first tumor (15 to 275 months; 95 % DI 72,15–111,66) and 32,88 months (from 0 to 154 months; 95 % DI 20,05– 45,71) after the onset of the second tumor. In general, from the beginning chemoradiotherapy first tumor patients lived an average of 85,85 months (from 12 to 264 months; 95 % DI 67,69–104,01). According to the classification of primary multiple tumors SM Slinchaka we identified subgroups of metachronous tumors: multicentric multiple tumors in one body — 30,9 % of patients; system tumors and tumor paired organs — 26,2 % of patients; nonsystem multiple tumors of various organs — 42,9 % of patients. For statistical processing results of the study, used the program IBM SPSS Statistics Version 22.0.0.0, Statistica Version 10.0.0.0.

The lack of a common methodological approach in the diagnosis of urinary tract damage and postoperative complications in gynecological and obstetric practice due to the limited possibilities of the existing methods of diagnosis. Purpose − to determine the effectiveness of multislice computed tomography (MSCT) in the diagnosis of iatrogenic lesions of the ureters and bladder in women during operations on the pelvic organs in obstetrics and gynecology. A comprehensive survey of 54 women aged 22 to 72 years with disease duration from 4 days to 19 years with various injuries of the urinary system. Patients underwent clinical, X-ray examination, ultrasonography (US), multislice computed tomography (MSCT). When MSCT obstruction level and nature of damage to the ureter, the presence of genitourinary fistula was identified in all studies. The incidence of X-ray examination of the ureter was identified in 40 %, the presence of urinary fistula – in 33,3 %, with the US lower third ureteral fistula course not visualized. MSCT of diagnostic efficacy superior to radiological techniques such as ultrasound and X-ray, and can be recommended as the primary method of diagnosing lesions of the ureters and bladder.

A method of obtaining high informative X-ray images with high geometric enlargement of the object is described in this work. Presently this method is not used for mammary gland diagnostic. Unlike the common methods of X-ray mammography in which the X-ray tube focal spot is about 100–300 μm and the coefficient of object enlargement is not more than two times. In the proposed method the X-ray tube with focal spot of about 25–50 μm is used that allows obtaining sharp X-ray images of mammary gland with coefficient of object enlargement of 3 to 10 times. Comparative researches using specialized mammography phantom allows to evaluate benefits of microfocus method compared with traditional methods. Images with 5-times object enlargement obtained using microfocus X-ray tubes have much higher information content and contain images of smaller and less contrastive structures than images obtained by traditional mammography. It may be significant for the correct and timely assessment of the pathologic process. It is shown that the exposure with multiply object enlargement allows using X-ray detectors with lower spatial resolution. It allows reducing the exposure dose by increasing the size of a digital detector’s pixel.

The article presents the results of the use of interstitial HDR brachytherapy as a component in the complex therapy for tongue cancer. In the period from November 2013 to may 2015 treated 7 patients diagnosed with locally spread cancer of the tongue. In 6 cases HDR brachytherapy were used in combination with external beam therapy and only 1 patient we used this method in independent form. As a result of the treatment 3 patients had a complete clinical remission, confirmed by MRI data and histological examination (follow-up period lasted 2–18 months). The recurrence of the tongue cancer with metastases in the lymph nodes of the neck was diagnosed in 1 patient (4 months after the end of treatment). In 3 patients during follow-up revealed recurrence in the lymph nodes of the neck.

We report on a rare clinical case of cerebral sinovenous thrombosis in a newborn with inherited thrombophilia. Thrombosis of transverse sinus was diagnosed on multiple view cranial ultrasonography and confirmed on CT and MRI.

The paper contains information about a clinical case the child with chronic cerebral ischemia caused by cerebral artery occlusion who was child surgical treated in our institute. The short literature review of surgical treatment in pediatric population occlusion the cerebral arteries and clinical case report of a successful stage-by-stage direct revascularization of the brain at the child combined with thrombofilia with good postoperative result is submitted.