No 3 (2019)
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ORIGINAL RESEARCH
M. G. Lapteva,
O. N. Sergeeva,
M. A. Shorikov,
D. Yu. Frantsev,
E. A. Kolosov,
E. R. Virshke,
B. I. Dolgushin
6-19 354
Abstract
Purpose - to identify MRI parameters suitable for assessment of metastatic neuroendocrine tumor (mNET) textural changes after liver transarterial chemoembolization (TACE) and their relationship with the progression-free survival. Thirty one hepatic mNET patients undergone 61 TACE procedures were enrolled in the study. One hundred eight pairwise (pre- and post-TACE) MRI studies were analyzed. Before and after TACE we measured apparent diffusion coefficient (ADC) and its standard deviation (SD), MR contrast agent (MRCA) uptake dynamics and signal intensity (SI) SD on portal phase T1 WI in the tumor solid component. The solid portions of target mNET demonstrate the following MRI changes after TACE: increase of ADC values (р = 0,002) and its SD (р = 0,006), decrease of MRCA accumulation on arterial (p = 0,016) and portal (p = 0,004) phases, increase of both MRCA wash-out time (p = 0,016) and SI SD on portal phase T1-WI (p = 0,026). The increase of ADC values and its SD and decrease in MRCA accumulation on portal phase were significantly associated with increase to progression free survival. Assessment of MRI parameters (ADC and MRCA accumulation) reflecting NET textural changes after liver TACE may be useful for accurate prediction of time to disease progression and personalization of MRI follow-up schedule.
20-28 375
Abstract
This study's aim is to evaluate the accuracy of CT volumetry in terms of predicting response to NAC in locally advanced GC. Pre- and post-chemotherapy volume of the tumor were measured using a dedicated 3D software (GE AW Volumeshare 5) and compared to histopathologic assessment of response. In patients with good response median tumor volume decrease was 54% vs 21% in patients with poor response, р < 0,0001. CT volumetry with a cut-off 37 % of tumor volume reduction predicts good morphological response after 3 cycles oof neoadjuvant chemotherapy in locally advanced gastric cancer with an overall accuracy of 92 %.
MEDICAL TECHNOLOGIES
30-40 354
Abstract
The paper presents a description of the nature of thermal processes and a method for metal structures heating evaluating in MRI, as well as the results of a series of experimental studies: passive implants and other metal objects were placed in the isocenter of the magnet and on the periphery, while being in the air, water, in gel or under heat insulating material. To study the heating, T2 FASE pulse sequence was used, and the temperature of the samples was recorded using fiber optic sensors. It is shown that the heating of metal structures is determined by both the properties of the object and the characteristics of the MR tomograph, as well as the scanning conditions, materials surrounding the object and its position in the MRI gantry. For the peripheral location of the phantom and an extended stainless-steel implant, a maximum heating of 2,5 °C was recorded in 15 minutes. When placed at the isocenter, the temperature of the samples increased by no more than 0,5 °C in 15 minutes, which indicates the possibility of conducting an MR study without exceeding the limitations associated with the amount of tissue heating. The results of the work demonstrate the necessity to take into account the magnitude of the possible heating of a metal object when deciding on the possibility of an MRI study for patients with metal structures.
CONTINUING MEDICAL EDUCATION
41-59 417
Abstract
Newborn acute appendicitis is an extremely rare disease, preoperative examination of which is almost always unsuccessful all over the world: the diagnosis is made based on operative or autopsy examination. Own clinical practice includes 4 cases of successful preoperative ultrasonic diagnosis of abdominal form of acute appendicitis (1 case - appendicular abscess and other 3 cases - of perforated appendix) and 15 cases of hernia Amyandmonitoring. All children were operated and recovered. Variants of visualization of the unchanged or reactively altered newborn appendix in addition to other diseases are presented. The article is supplemented by an extensive review of the literature.
60-76 322
Abstract
In cases of multiple bilobar lesions of the liver, in the absence of the possibility of surgical treatment, one of the methods of treatment is polychemotherapy which carrying out requires not only biochemical control, but also control of using the capabilities of radiological diagnostic methods. Magnetic resonance imaging allows conducting a dynamic comparison of tumors with regard to generally accepted recommendations. In the arsenal of the method there are also techniques, the data of which are not included in the well-known recommendations, the use of which can make a contribution to the conclusion of the study.
ISSN 2713-0118 (Online)