Results of treatment of 49 patients were analyzed. All patients were undergone on breast-conserving surgery with intraoperative digital specimen radiography. Positive margins were detected in 2 cases. Additional excision helped to avoid reoperation. In 2 cases, false positive results were obtained, which had not affect adversely on the treatment results. False negative results were not found. Considering frequent inconsistency between macro and microscopic states, the determination of the carcinoma in situ borders appeared to be the most difficult.

The relevance of the study is determined by the frequency of pleural effusion in children not only with pulmonological diseases, but also in a wide variety of patients with different multiple organ problems. Echographic criteria for assessing pleural contents of various etiologies are not always accurate, and quantitative assessment of pleural effusion in children's practice has not yet been developed. Schemes adopted in adult practice cannot be applied in children's practice, especially in young children. The article shows options for echographic representation of various types of pleural effusion, analyzes the use of various forms of calculating the volume of pleural effusion, and suggests correction factors for children of different weights.

Based on a clinical example, the importance of timely diagnosis of breast cancer in a patient with a negative mammograms, but with minimal changes in the organ tissue according to ultrasound data is shown. The pathological focus was located on the border of the inner quadrants of the breast at the edge of the parasternal line, which is rare. Oncology vigilance and violation of the scanning methodology did not allow specialists of the outpatient-polyclinic level of general profile to identify the existing changes in the breast tissue (diagnostic iatrogeny). Repeated examination of the patient in a specialized medical institution revealed breast cancer 0,5 × 0,4 × 0,3 cm in size, which made it possible to further de-escalate the surgical stage of treatment and preserve both the social activity of the woman and obtain good cosmetic results.

In spite of asymmetric malocclusion being highly prevalent in the overall population, its etiology remains partly unknown. We examined morphology and position of the sphenoid bone, maxilla and mandible on cone-beam computed tomograms of patients with asymmetric malocclusion. Correlation analysis was performed. Obtained results show that particular aspects of sphenoid morphology and position might lead to asymmetric malocclusion.

The aim was to study the possibilities and compare the diagnostic efficiency of computed tomography performed according to the standard protocol and using a perfusion program in detecting pancreatic adenocarcinoma. The study included 94 (58,4 %) men and 67 (41,6 %) women aged from 28 to 96 years (71,8 ± 12,4 years) with pancreatic adenocarcinoma verified by histological examination. All patients underwent computed tomography of the abdominal organs according to the standard protocol and using a perfusion program. With the standard protocol, tumors appeared as a focus of reduced contrast agent accumulation in the pancreatic phase in 123 (76,4 %) patients, did not differ in density and intensity of contrast agent accumulation from the pancreatic parenchyma in all phases in 38 (23,6 %) patients. The diagnostic efficiency of the standard protocol in detecting pancreatic adenocarcinoma was as follows: sensitivity - 95,8 %, specificity - 98,7 %, diagnostic accuracy - 94,7 %. With perfusion computed tomography, the tumor could not be visualized only in 2 (1,2 %) of 161 patients, the diagnostic efficiency of the method was: sensitivity 98,7 %, specificity 99,3 %, diagnostic accuracy 99 %, was higher in comparison with standard protocol.

In December 2019 humanity faced a new infectious disease caused by SARS-CoV-2, a strain of coronavirus. A more detailed study of the pathology showed that this pathogen affects not only the lung tissue, but also other target organs: the brain, heart, gastrointestinal tract, joints, kidneys. Myocarditis after coronavirus infection is the most discussed problem among cardiologists. Postponed COVID-19, even a mild course, is associated with a high risk of heart muscle damage in a delayed period. Conducting MRI of the heart with delayed contrast enhancement allows detecting myocarditis in patients who have undergone coronavirus infection, assessing the functional and prognostic consequences of the disease.