The coronavirus of severe acute respiratory syndrome-2 (SARS-CoV-2) and the coronavirus infection caused by it, along with damage to the respiratory system, can lead to disorders of the central and peripheral nervous system. The article presents literature data and own observations of neurological disorders in patients with coronavirus disease in the superacute period. Pronounced neurological disorders are mainly observed in severe coronavirus disease and include acute ischemic stroke, subcortical micro- and macro— bleeding, acute necrotizing encephalopathy, Guillain-Barre syndrome. Factors potentially complicating the course of coronavirus disease and contributing to the development of neurological complications are hypertension, diabetes mellitus, chronic diseases of the heart and respiratory system. Based on existing publications and our own observations, we have systematized information about the relationship between coronavirus disease and neurological disorders, about possible factors contributing to the occurrence of stroke. The possibilities of using chest MSCT as the only method of radiation diagnostics for the early detection of viral pneumonia in patients receiving emergency and emergency care at the regional vascular center of BUZOO «GC BSMP No. 1» are considered. The use of this method, in the ultra-acute period of acute ischemic stroke, during the first 40 minutes from the moment of admission, can significantly reduce the time of diagnosis and mortality in patients with acute ischemic stroke and viral pneumonia.

The  history of subchondral insufficiency fracture of knee is closely related to a pre-existing diagnosis of  spontaneous osteonecrosis (SONK). Previously,  it  was believed that  subchondral linear or lunate pathological changes on magnetic resonance imaging in elderly patients with osteoporosis are the result of spontaneous osteonecrosis that has occurred, but it was later found that a small proportion of patients with osteonecrosis of the femoral head initially  have a failure fracture, then complicated by secondary osteonecrosis. The main methods for diagnosing subchondral insufficiency fracture are radiography and magnetic resonance imaging. Magnetic  resonance imaging has demonstrated high information content in subchondral insufficiency fracture of knee.

Lemierre syndrome is extremely rare and poorly known to medical practitioners. In  childhood, this is completely casuistry, described almost exclusively in adolescents. The  key component of the syndrome is jugular vein thrombosis and sinus thrombosis, which develop against the background of polysinusitis and  purulent  otitis  and  are also  accompanied by  the  addition  of  pneumonia, meningitis  and  sepsis. Typically,  Lemierre’s syndrome is considered otogenic or sinusogenic sepsis. The nonspecificity of clinical manifestations against the background of the patient’s severe general condition determines the need for quick and accurate diagnosis, and ultrasound takes the first place in a series of radiation research methods, which allows differentiating jugular vein thrombosis. When the latter is found, MRI and CT are usually performed, in which  the presence of sinus thrombosis, inflammatory changes in the paranasal sinuses, pneumonia, etc. are usually confirmed. Further clinical and laboratory examination is designed to assess the presence of meningitis and a violation of the blood coagulation system. This publication provides 3 atypical observations of Lemierre’s syndrome in children: in the first case, it was thrombosis of the jugular vein that was first detected in an adolescent, and only then all other components of the syndrome; in the second case, the child was only 3 years old, which is completely atypical for this pathology, the third patient was 1 month old, and the diagnosis of Lemierre syndrome was made retrospectively. All children underwent a complex radiation examination, operated on, received massive syndrome therapy and were discharged home with recovery. The publication is extensively illustrated and contains a brief overview of the literature.

Tuberous sclerosis (TBS) is a genetically determined orphan disease when many benign tumors (hamartomas) are formed in various organs and systems. The complexity of diagnosis is associated with a wide variety of clinical forms of the disease. Despite the benign nature of hamartomas, they cause dysfunction of the body, which leads to disability and a reduction in the life expectancy of patients. The lesions of the brain and heart are most characteristic for the early onset of the disease in infants and neonatal children. The article presents morphological changes in the central nervous system and heart, compares these changes with ultrasound and magnetic resonance imaging data. With the help of two clinical cases, the high sensitivity of neurosonography, as the primary method of examination of the brain, and the possibility of early diagnostics of the tuberous-sclerosis complex are shown. The publication also contains a literature review, clinical and diagnostic criteria of tuberous sclerosis, brief information about pathogenetic treatment in young children and a large number of illustrations.

Intestinal intussusception in a newborn is a casuistic rarity, the clinical symptoms of which are nonspecific, and patients are regarded for a relatively long time as patients with necrotic enterocolitis. There are no unambiguous radiological signs of this  pathology,  especially with  atypical  variants of intussusception, when even pneumoirrigography is uninformative. In the vast majority of cases, the diagnosis is made only intra-operatively, when the development of intestinal obstruction or perforated peritonitis determines the need for surgical intervention. The publication presents a unique observation of preoperative echographic diagnosis and successful cure of prolonged small-intestinal invagination in a premature newborn 2 days of life, the cause of which was Meckel’s diverticulum.

A clinical example is presented that demonstrates the capabilities of magnetic resonance imaging (MRI) in the diagnosis of kidney damage and their complications at different periods of traumatic disease. An optimized MRI protocol has been demonstrated, which allows for timely diagnosis of kidney damage and determines the treatment regimen.

Hippel-Lindau  disease is a rare hereditary combined pathology characterized by development of a variety of benign and malignant tumors in the central nervous system, kidneys, pancreas, adrenal glands, which causes a wide range of clinical manifestations. A comprehensive diagnostic approach using various imaging techniques such as ultrasound, magnetic resonance imaging, computed tomography, and genetic testing is an integral part of successful treatment.