Aim. To demonstrate the possibilities of radiation examination of late complications of some types of cosmetic breast surgery.

Materials and methods. A few clinical examples demonstrate certain types of late complications of aesthetic breast surgery.

Conclusion. It is advisable to carry out a preoperative examination in a specialized medical and diagnostic institution in compliance with all the canons of early diagnosis of breast cancer. Cases of breast cancer omissions at the pre- and postoperative stages of aesthetic surgery require further investigation.

Objective. To determine a possible assessment of the verification of the genetic group of medulloblastomas based on MRI imaging and quantitative assessment indicators.

Materials and Methods. MRI data of 60 patients with a verified molecular genetic subgroup based on the expression level of selected genes on the Nano String platform were retrospectivel analyzed.

Results. Based on MRI signs of the shape and contrast intensity of the tumor, taking into account the age of the patients, 76 % of medulloblastomas were correctly identified by genetic groups.

Conclusion. The ability to predict the genetic group of the disease in children with medulloblastoma during an initial MRI study with an accuracy of 76 % seems to us important and relevant. Only the first steps have been taken in the development of radiogenomics of medulloblastomas in children.

The classification of CNS tumors with the molecular subgroups of medulloblastomas has allowed modern pediatric oncological practice to apply a differentiated approach to stratification of risk groups and prognosis of the disease. This affects the determination of the scope and the tactics of treatment. The aim of our study was an attempt to systematize and definition the diagnostic radiological signs of the currently known four molecular subgroups of medulloblastomas in children. Thirty-nine (76%) patients diagnosed with medulloblastoma were correctly classified into genetic groups based on radiographic features of shape, contrast intensity, and patient age.

Objective. To determinate the significance of diffusion-weighted imaging and ASL-perfusion in evaluation the progression of chronic kidney disease.

Materials and methods. The study included 77 patients with chronic kidney disease: 34 (44.2 %) men and 43 (55.8 %) women. All subjects underwent Magnetic Resonance Imaging of the kidneys, with the inclusion of diffusion-weighted imaging (DWI) and ASL (arterial spinal label) perfusion in the research protocol. These results helped divide the patients into three groups. The comparison group included 61 healthy people.

Results. There is statistically significant difference data in DWI and ASL perfusion between patients with CKD and the comparison group. The comparison group has the next counts: no diffusion restriction, ADC is 4.8 ± 0.1 × 10-3 mm2 /s, ASL-perfusion is 482–496 ml/100 g/min. The first group has no diffusion restriction, ADC is 1–4 × 10-3 mm2 /s, ASL-perfusion is 390–436 ml/100 g/min, the second group has no diffusion restriction, ADC is more than 4 × 10-3 mm2 /s and ASL-perfusion 294–402 ml/100 g/min. The third group has diffusion restriction with different ADC and ASL-perfusion.

Conclusion. Absence of diffusion restriction, ADC is 1–4 × 10-3 mm2 /s, ASL-perfusion is 390–436 ml/100 g/min is indication of the beginning of injury to intact nephrons, the stage of hyperfiltration (r = 0,973). Absence of diffusion restriction, ADC is more than 4 × 10-³ mm2 /s and ASL-perfusion 294–402 ml/100 g /min is risk of metabolic disorders in CKD (r = 0,981). If it has diffusion restriction with different ADC and ASL-perfusion, there is high correlation with CKD stage 3b (r = 0.923) and hypokalemia (r = 0.988). DWI and ASL perfusion must be included in the examination algorithm for patients with CKD to create a personalized diagnostic and treatment algorithm.

Background. Ingestion of magnetic foreign bodies (MFBs) in pediatric practice has become common in recent years due to the prevalence of toys containing magnets. Ingestion of one small MFB rarely causes damage to the gastrointestinal tract (GIT). However, with the non-simultaneous ingestion of multiple MFBs, there is a risk of complications (intestinal perforation, formation of infiltrate, development of intestinal obstruction, peritonitis), which determines the importance of accurate diagnosis and active surgical tactics for patient management.

Objective. Demonstration of the capabilities of ultrasound diagnostics in detecting fixed MFBs of the digestive tract in children.

Materials and Methods. Two clinical observations of MFBs are presented: in the first case, the absence of passage of MFBs through the GIT in an 8-year-old child was the reason for a targeted ultrasound search for magnets with determination of their localization. In the second case, in a 2.5-year-old girl, long-standing MFBs in the GIT simulated the clinical picture of celiac disease due to the formation of gastrointestinal fistulas. The children underwent X-ray examination and ultrasound.

Results. In the first case, echographically it was possible to clearly differentiate the location of MFBs in the lumen of the colon; in the second case, fixed MFBs were echographically differentiated in the upper parts of the abdominal cavity. Complex radiological diagnostics made it possible to optimize the tactics of patient management: in the first case, MFBs were successfully removed during colonoscopy; in the second observation, endoscopic removal of 3 MFBs from the stomach and laparoscopic removal of 24 MFBs from the small intestine and large intestine and separation of interintestinal anastomoses were performed. Both children recovered.

Conclusion. Ultrasound can be recommended as an additional diagnostic method for MFBs of the digestive tract in children to clarify the localization of MFBs and assess complications. Performing an ultrasound is advisable after an X-ray examination, when the approximate localization of MFBs is known.

A clinical example is presented that demonstrates the capabilities of an additional magnetic resonance 3D-FSE (3D-PD-FS-WI) of complete and partial ruptures of the supraspinatus tendon of the shoulder. The article provides an MRI protocol that allows for successful diagnosis of these rupture types.

Aim. Demonstration of the diagnostic capabilities of the additional submillimeter isotropic mode 3D-FSE (3D-PD-FS-WI) in the MRI diagnosis of complete and partial tears of the supraspinatus tendon.

Clinical case. A clinical case of the successful use of submillimeter isotropic 3D-FSE mode (3D-PD-FS-WI) in a patient with a rupture of the supraspinatus tendon is demonstrated.

Conclusion. The 3D-FSE (3D-PD-FS-WI) mode demonstrated: excellent detailing of the rupture zone, the ability to assess pathology in any plane using a 3D cursor and more suitable «showing» of pathology in the desired plane.

Aim. To investigate the capabilities of comprehensive assessment using ultrasound and magnetic resonance imaging (MRI) of the results of cosmetic procedures.

Materials and Methods. A study of the soft tissues of the anterior abdominal wall of a 43-year-old woman complaining of skin atony and postpartum stretch marks using highresolution ultrasound and MRI.

Results. At ultrasonography in the projection of injection of polylactic acid and calcium hydroxyapatite preparations and radiofrequency treatment, an increase in echogenicity of hypodermis with the presence of acoustic shadow was noted. On MRI at the level of derma and hypoderma of periumbilical region in the projection of radiofrequency treatment, injections of preparations based on polylactic acid on the left, calcium hydroxyapatite on the right in 3 months after subdermal injection, areas of hyperintense MR-signal in T2 weight image (WI) and STIR programs, hypointense in T1 WI, without diffusion limitation on DWI b=1000 were determined. In SWI mode, the focus of hypointense MR signal of rounded shape with clear and smooth contours was visualized on the right side of the image.

Conclusion. The clinical study demonstrates the possibilities of an integrated approach in evaluating the results of cosmetic procedures using ultrasonography and MRI.